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surveillance studies

  • <em>In Vitro</em> Activity of Sulbactam-Durlobactam against <span class="named-content genus-species" id="named-content-1">Acinetobacter baumannii</span>-<em>calcoaceticus</em> Complex Isolates Collected Globally in 2016 and 2017
    Epidemiology and Surveillance
    In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017

    Acinetobacter baumannii-calcoaceticus complex (ABC) organisms cause severe infections that are difficult to treat due to preexisting antibiotic resistance. Sulbactam-durlobactam (formerly sulbactam-ETX2514) (SUL-DUR) is a β-lactam–β-lactamase inhibitor combination antibiotic designed to treat serious infections caused by ABC organisms, including multidrug-...

    Sarah M. McLeod, Samir H. Moussa, Meredith A. Hackel, Alita A. Miller
  • Open Access
    <em>In Vitro</em> Activity of Cefepime-Enmetazobactam against Gram-Negative Isolates Collected from U.S. and European Hospitals during 2014–2015
    Epidemiology and Surveillance
    In Vitro Activity of Cefepime-Enmetazobactam against Gram-Negative Isolates Collected from U.S. and European Hospitals during 2014–2015

    Enmetazobactam, formerly AAI101, is a novel penicillanic acid sulfone extended-spectrum β-lactamase (ESBL) inhibitor. The combination of enmetazobactam with cefepime has entered clinical trials to assess safety and efficacy in patients with complicated urinary tract infections.

    Ian Morrissey, Sophie Magnet, Stephen Hawser, Stuart Shapiro, Philipp Knechtle
  • Geographic Mapping of <span class="named-content genus-species" id="named-content-1">Escherichia coli</span> Susceptibility To Develop a Novel Clinical Decision Support Tool
    Epidemiology and Surveillance
    Geographic Mapping of Escherichia coli Susceptibility To Develop a Novel Clinical Decision Support Tool

    Antimicrobial resistance (AMR) varies regionally. This study longitudinally maps Escherichia coli susceptibility leveraging Wisconsin antibiograms (n = 202) collected from 2009, 2013, and 2015 to inform the development of a novel clinical decision support tool.

    Laurel Legenza, Susanne Barnett, James P. Lacy, Codie See, Natalee Desotell, Andrea Eibergen, Jeffrey F. Piccirillo, Warren E. Rose
  • Open Access
    Epidemiology and Surveillance
    Increasing Antimicrobial Resistance in Nontyphoidal Salmonella Isolates in Australia from 1979 to 2015
    Deborah A. Williamson, Courtney R. Lane, Marion Easton, Mary Valcanis, Janet Strachan, Mark G. Veitch, Martyn D. Kirk, Benjamin P. Howden
  • Epidemiology and Surveillance
    In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa Isolated by Clinical Laboratories in 40 Countries from 2012 to 2015
    James A. Karlowsky, Krystyna M. Kazmierczak, Boudewijn L. M. de Jonge, Meredith A. Hackel, Daniel F. Sahm, Patricia A. Bradford
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