tolerance
Clinical TherapeuticsA First-in-Human Safety, Tolerability, and Pharmacokinetics Study of Benapenem in Healthy Chinese VolunteersThe objective of this trial was to investigate the safety, tolerability, and pharmacokinetics (PK) of benapenem administered by single or multiple intravenous infusions in healthy Chinese volunteers. The trial was divided into 3 parts.
- Mechanisms of Action: Physiological EffectsRelationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System
- Mechanisms of Action: Physiological EffectsSuppression of Reactive Oxygen Species Accumulation Accounts for Paradoxical Bacterial Survival at High Quinolone Concentration
- Mechanisms of ResistanceThe Two-Component System ChtRS Contributes to Chlorhexidine Tolerance in Enterococcus faecium
- Mechanisms of Action: Physiological EffectsSubinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams
- Mechanisms of ResistanceIn Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin