Trans-Activators

Mechanisms of Resistance
Roles of ramR and tet(A) Mutations in Conferring Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates
Sheng-Kang Chiu, Li-Yueh Huang, Hsi Chen, Yu-Kuo Tsai, Ci-Hong Liou, Jung-Chung Lin, L. Kristopher Siu, Feng-Yee Chang, Kuo-Ming Yeh
Mechanisms of Resistance
Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin
Julien Bador, Catherine Neuwirth, Nadège Grangier, Marie Muniz, Leslie Germé, Jérémy Bonnet, Vignesh-Guru Pillay, Catherine Llanes, Claire de Curraize, Lucie Amoureux
Mechanisms of Resistance
Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump
Q. C. Truong-Bolduc, Y. Wang, C. Chen, D. C. Hooper
Mechanisms of Resistance
Requirement of the CroRS Two-Component System for Resistance to Cell Wall-Targeting Antimicrobials in Enterococcus faecium
Stephanie L. Kellogg, Jaime L. Little, Jessica S. Hoff, Christopher J. Kristich
Biologic Response Modifiers
VraR Binding to the Promoter Region of agr Inhibits Its Function in Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA
Yuanyuan Dai, Wenjiao Chang, Changcheng Zhao, Jing Peng, Liangfei Xu, Huaiwei Lu, Shusheng Zhou, Xiaoling Ma
Mechanisms of Resistance
Structural Alteration of OmpR as a Source of Ertapenem Resistance in a CTX-M-15-Producing Escherichia coli O25b:H4 Sequence Type 131 Clinical Isolate
Hervé Dupont, Pascaline Choinier, David Roche, Sandine Adiba, Megan Sookdeb, Catherine Branger, Erick Denamur, Hedi Mammeri
Pharmacology
Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin
Zackery P. Bulman, Neang S. Ly, Justin R. Lenhard, Patricia N. Holden, Jürgen B. Bulitta, Brian T. Tsuji
Mechanisms of Action: Physiological Effects
Subinhibitory Concentrations of Protein Synthesis-Inhibiting Antibiotics Promote Increased Expression of the agr Virulence Regulator and Production of Phenol-Soluble Modulin Cytolysins in Community-Associated Methicillin-Resistant Staphylococcus aureus
Hwang-Soo Joo, June L. Chan, Gordon Y. C. Cheung, Michael Otto
Antiviral Agents
The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein
Arianna Loregian, Beatrice Mercorelli, Giulia Muratore, Elisa Sinigalia, Silvana Pagni, Serena Massari, Giorgio Gribaudo, Barbara Gatto, Manlio Palumbo, Oriana Tabarrini, Violetta Cecchetti, Giorgio Palù
Mechanisms of Action: Physiological Effects
Constitutive SoxS Expression in a Fluoroquinolone-Resistant Strain with a Truncated SoxR Protein and Identification of a New Member of the marA-soxS-rob Regulon, mdtG
Anna Fàbrega, Robert G. Martin, Judah L. Rosner, M. Mar Tavio, Jordi Vila

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