urinary

  • <em>In Vitro</em> Activity of Sulopenem, an Oral Penem, against Urinary Isolates of <em>Escherichia coli</em>
    Susceptibility
    In Vitro Activity of Sulopenem, an Oral Penem, against Urinary Isolates of Escherichia coli

    The in vitro activity of sulopenem was assessed against a collection from 2014 to 2016 of 539 urinary isolates of Escherichia coli from Canadian patients by using CLSI-defined broth microdilution methodology. A concentration of sulopenem 0.03 µg/ml inhibited both 50% (MIC50) and 90% (MIC90) of isolates tested; sulopenem MICs ranged from...

    James A. Karlowsky, Heather J. Adam, Melanie R. Baxter, Andrew J. Denisuik, Philippe R. S. Lagacé-Wiens, Andrew J. Walkty, Sailaja Puttagunta, Michael W. Dunne, George G. Zhanel
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