virtual screening
Chemistry; BiosynthesisPromising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensisParacoccidioidomycosis (PCM), caused by Paracoccidioides, is a systemic mycosis with granulomatous character and a restricted therapeutic arsenal. The aim of this work was to search for new alternatives to treat largely neglected tropical mycosis, such as PCM.