Yersinia pestis
Experimental TherapeuticsActivation of Heme Oxygenase Expression by Cobalt Protoporphyrin Treatment Prevents Pneumonic Plague Caused by Inhalation of Yersinia pestisPneumonic plague, caused by the Gram-negative bacteria Yersinia pestis, is an invasive, rapidly progressing disease with poor survival rates. Following inhalation of Y. pestis, bacterial invasion of the lungs and a tissue-damaging inflammatory response allows vascular spread of the infection....
- Experimental TherapeuticsCombating Multidrug-Resistant Pathogens with Host-Directed Nonantibiotic Therapeutics
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